Advanced Signal-Processing for Ultra-Fast Magnetic Resonance
Menu Content/Inhalt
Home arrow Public articles arrow Scientific documents arrow A metabolomics perspective of human brain tumours
A metabolomics perspective of human brain tumours PDF Print E-mail

Attached is a review article article FEBS Journal 274 (2007) 1132-1139,

 A metabolomics perspective of human brain tumours
Julian L. Griffin1 and Risto A. Kauppinen2
1 Department of Biochemistry, University of Cambridge, UK
2 School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, UK

Abstract: 

 During the past decade or so, a wealth of information about
  metabolites in various human brain tumour preparations (cultured
  cells, tissue specimens, tumours in vivo) has been accumulated by
  global profiling tools. Such holistic approaches to cellular
  biochemistry have been termed metabolomics.
  Inherent and specific metabolic profiles of major brain tumour cell
  types, as determined by PROTON NUCLEAR MAGNETIC RESONANCE
  SPECTROSCOPY (H-1 MRS), HAVE ALSO BEEN USED TO DEFINE METABOLITE
  PHENOTYPES IN TUMOURS IN VIVO.
  This minireview examines the recent advances in the field of human
  brain tumour metabolomics research, including advances in MRS and
  mass spectrometry technologies, and data analysis.

The full text is in griffin07.pdf.