Marie Curie Fellows :: Partner 10 - Brno, Czech Republic
Marie-Curie Fellow
Research & Training Network
O. Strbak (ESR)
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Marie Curie Fellow (ESR) of the FAST project
Institute of Scientific Instruments of the Academy of Sciences of the Czech Republic, Brno
Contact
| Involved in the following tasks |
T3 Virtual scanner
Task 3 concerns the development of the Virtual Scanner. The NMR-SCOPE software (developed in UCBL) constitutes the starting point of this activity. This research will enable quantum-mechanical simulation of in vivo MRSI signals from spin Hamiltonian parameters for diverse, user-adaptable, measurement protocols that include, e.g., `spectral editing' and 2D-MRS. The spin Hamiltonian parameters in turn, can be derived from high-resolution, spatially-resolved, `magic angle spinning' ex vivo NMR, or from ab initio quantum-mechanical calculations. Note that computing power grows unabated, enabling simulation of increasingly complicated spin systems and experimental conditions. This new opportunity is to be exploited to the full. The simulated MRSI-signals serve as metabolite reference database to be used in Task T4. Finally, a contract with NIH concerning cooperation on this subject, has recently been concluded.
To my responsibilities in the network belongs develop algorithms and software providing virtual scanner functionality by simulating the quantum-mechanical behaviour of J-coupled, relaxing and spatially distributed spin systems excited by pulses. This tool will support the clinical user (the predicted spectra of individual metabolites excited by specific pulse sequences will form a base for signal analysis) as well as the research user (simulation of spatial and spectral selectivity, artifacts, method robustness, needed for pulse sequence design). Also I participate in NMR experimental work (MRI & MRS of biological samples).
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- Starcuk Z, Strbak O, Starcukova J and Graveron-Demilly D, Modification of the QuaM-EPG method for the simulation of coupled spin systems in RARE-based imaging and fast spectroscopic imaging methods, In European Society for Magnetic Resonance in Medicine and Biology ESMRMB 2009, #77, Antalya Turkey, October 1-3 2009
- Starcuk Z jr, Starcukova J, Strbak O and Graveron-Demilly D, Simulation of coupled spin systems in steady state free precession acquisition mode for fast MR spectroscopic imaging, Measurement Science and Technology 20 #104033 (2009)
- Stefan D, Di Cesare F, Andrasecu A, Popa E, Lazariev A, Vescovo E, Strbak O, Williams S, Starcuk Z, Cabanas M, van Ormondt D and Graveron-Demilly D, Quantitation of magnetic resonance spectroscopy signals: the jMRUI software package, Measurement Science & Technology 20(10) #104035 (2009)
- Starcuk Z jr, Starcukova J, Strbak O and Graveron-Demilly D, Quantum mechanical generalization of the Extended Phase Graph method (QuaM-EPG) for the simulation of coupled spin systems under SSFP excitation, In International Society for Magnetic Resonance in Medicine ISMRM 2009, #4291, Honolulu Hawaii USA, April 18-24 2009
- Stefan D, Andrasecu A, Popa E, Lazariev A, Strbak O, Starcuk Z, Cabanas M, van Ormondt D and Graveron-Demilly D, jMRUI Version 4: A Plug-in platform, In International Society for Magnetic Resonance in Medicine ISMRM 2009, #4340, Honolulu Hawaii USA, April 18-24 2009
- Starcuk Z, Strbak O, Starcukova J and Graveron-Demilly D, Simulation of steady state free precession acquisition mode in coupled spin systems for fast MR spectroscopic imaging, 2008 IEEE International Workshop on Imaging Systems and Techniques, pp 300-304, Chania Island of Crete Greece, September 10-11 2008
- Stefan D, Andrasecu A, Popa E, Rabeson H, Strbak O, Starcuk Z, Cabanas M, van Ormondt D and Graveron-Demilly D, jMRUI Version 4: A Plug-in Platform, 2008 IEEE International Workshop on Imaging Systems ans Techniques, pp 344-346, Chania Island of Greece, September 10-11 2008
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